Journal:

Article Title: Operational correlates of prostanoid TP receptor expression in human non-pregnant myometrium are unaffected by excision site or menstrual cycle status of the donor

doi: 10.1038/sj.bjp.0702964

Figure Lengend Snippet: (a) Sample trace showing the effect of cumulative addition of U46619 on the contractile activity of a strip of myometrium excised from the top of the corpus uteri from a non-pregnant donor in the proliferative phase of the menstrual cycle. Horizontal bars indicate 10 min collection periods, the first of which is the control. Thereafter, U46619 was added to the baths at the points indicated by the arrows to give the cumulative concentrations shown. (b) Concentration-effect curve, constructed from the data in (a).

Article Snippet: Compounds U46619 ([1R-[1a,4a,5b(Z),6a(1E,3S*)]]-7-[6-(3-hydroxy-1-octenyl)-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid), [ 125 I]-BOP and IBOP ([1S[1α,2α(Z),3β(1E,3S * ),4α)]]-7-[3-[3-hydroxy-4-(4-iodophenoxy)-1-butenyl]-7-oxabicyclo-[2.2.1]hept-2 - yl]5 - heptanoic acid) were purchased from Cayman Chemical (Ann Arbor, MI, U.S.A.).

Techniques: Activity Assay, Stripping Membranes, Control, Concentration Assay, Construct

Journal:

Article Title: Operational correlates of prostanoid TP receptor expression in human non-pregnant myometrium are unaffected by excision site or menstrual cycle status of the donor

doi: 10.1038/sj.bjp.0702964

Figure Lengend Snippet: Effect of excision site, orientation and menstural cycle status of the donor on U46619-induced contractile activity of human non-pregnant myometrium

Article Snippet: Compounds U46619 ([1R-[1a,4a,5b(Z),6a(1E,3S*)]]-7-[6-(3-hydroxy-1-octenyl)-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid), [ 125 I]-BOP and IBOP ([1S[1α,2α(Z),3β(1E,3S * ),4α)]]-7-[3-[3-hydroxy-4-(4-iodophenoxy)-1-butenyl]-7-oxabicyclo-[2.2.1]hept-2 - yl]5 - heptanoic acid) were purchased from Cayman Chemical (Ann Arbor, MI, U.S.A.).

Techniques: Activity Assay